Description
Benefits
- Supports immune system regulation and balance
- May help reduce chronic inflammation
- Promotes endogenous endorphin production
- Commonly used in autoimmune and inflammatory conditions
- May support metabolic signaling and appetite regulation
- Often incorporated into longevity and wellness-focused protocols
Background and History
- Naltrexone was originally developed and approved at higher doses for opioid and alcohol dependence
- Clinicians later observed unique immune and anti-inflammatory effects at much lower doses
- Low-dose use was found to influence endorphin signaling and immune modulation
- Endorphins play a role in immune tolerance, inflammation control, and cellular resilience
- LDN gained popularity in autoimmune and chronic inflammatory settings due to its favorable tolerability
- Today, it is widely used in compounded form as part of individualized longevity, immune, and metabolic-health protocols
Compounded, non-FDA-approved medication. Individual results may vary.
